In vitro transcorneal and transscleral diffusion of radiolabeled compounds in human and rabbit cornea and in human, monkey, dog, and rabbit sclera

@inproceedings{Struble2009InVT,
  title={In vitro transcorneal and transscleral diffusion of radiolabeled compounds in human and rabbit cornea and in human, monkey, dog, and rabbit sclera},
  author={C. Struble and Hf Edelhauser and Gp Holley and He Grossniklaus},
  year={2009}
}
Purpose To determine the in vitro diffusion of selected compounds across the cornea or sclera of humans, monkeys, dogs, and rabbits. Methods Human and NZW rabbit corneas were obtained and the epithelium was removed from one cornea of each pair. Corneas were mounted in chambers with 3H-water or 3H-dexamethasone on the epithelial side and BSS solution on the endothelial side. Serial aliquots were taken from each chamber and assayed by LSC. Scleral sections from human, NZW rabbit, dog, or… CONTINUE READING