In vitro thrombolytic activity of a purified fibrinolytic enzyme from Chlorella vulgaris.

@article{Silva2018InVT,
  title={In vitro thrombolytic activity of a purified fibrinolytic enzyme from Chlorella vulgaris.},
  author={Pablo Eug{\^e}nio Costa e Silva and Rafaela Cavalcante de Barros and Wendell Wagner Campos Albuquerque and Romero Marcos Pedrosa Brand{\~a}o and Raquel Pedrosa Bezerra and Ana L{\'u}cia Figueiredo Porto},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2018},
  volume={1092},
  pages={
          524-529
        }
}
  • Pablo Eugênio Costa e Silva, Rafaela Cavalcante de Barros, +3 authors Ana Lúcia Figueiredo Porto
  • Published 2018
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  • A fibrinolytic enzyme was produced by microalga Chlorella vulgaris cultivated in autotrophic and mixotrophic conditions added corn steep liquor, purified by a single chromatographic step, then biochemical characterization and in vitro thrombolytic activity was performed. Maximum cell concentration (1637.45 ± 15 mg L-1) and productivity (181.93 mg L-1 day-1) was obtained in mixotrophic culture using 1% corn steep liquor. Enzyme-extracted microalgal biomass was purified by acetone precipitation… CONTINUE READING

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