In vitro systems for coupling RNAP II transcription to splicing and polyadenylation.

Abstract

Studies over the past several years have revealed that steps in gene expression are extensively coupled to one another both physically and functionally. Recently, in vitro systems were developed for understanding the mechanisms involved in coupling transcription by RNA polymerase II to RNA processing. Here we describe an efficient two-way system for… (More)
DOI: 10.1007/978-1-62703-980-2_13

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