In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp.

@article{Arikan2002InVS,
  title={In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp.},
  author={Sevtap Arikan and Mario Lozano-Chiu and Victor L Paetznick and John Rex},
  journal={Antimicrobial agents and chemotherapy},
  year={2002},
  volume={46 1},
  pages={245-7}
}
We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and FUSARIUM: Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines in Antibiotic Medium 3 broth supplemented to 2% glucose. Antagonism was not observed for any of the isolates tested. Caspofungin and amphotericin B were synergistic or synergistic to additive for at least half of the isolates. 

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