In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.

Abstract

Classical chemotherapy has an active, but limited, role in acute leukemia with relapse common in adult patients. Recent evidence has implicated signal transduction pathways in leukemic progression and also in resistance to cytotoxic therapy. We have used a short-term, in-vitro incubation assay with cytotoxic analysis by MTT, confirmed by histone-associated… (More)
DOI: 10.1097/CAD.0b013e328304ae19

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Cite this paper

@article{Calabro2008InvitroSO, title={In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.}, author={Anthony Calabro and Julia C. Tai and Steven L. Allen and Daniel R. Budman}, journal={Anti-cancer drugs}, year={2008}, volume={19 7}, pages={705-12} }