In vitro suppression assay for functional assessment of human regulatory T cells.

@article{Tran2013InVS,
  title={In vitro suppression assay for functional assessment of human regulatory T cells.},
  author={Dat Q Tran},
  journal={Methods in molecular biology},
  year={2013},
  volume={979},
  pages={199-212}
}
FOXP3(+) regulatory T cells (Tregs) play an important role in controlling immune activation, maintenance of -homeostasis and the prevention of autoimmunity. Much effort has been focused in assessing their potential defects in certain human diseases and in developing potential Treg immunotherapy to cure autoimmune conditions. One cardinal feature of Tregs is their ability to suppress the activation and proliferation of effector T cells. The in vitro suppression assay is a convenient and… CONTINUE READING