In vitro study of the carry-over effect associated with early diabetic embryopathy in the rat

@article{Pampfer1994InVS,
  title={In vitro study of the carry-over effect associated with early diabetic embryopathy in the rat},
  author={Serge Pampfer and Yd. Wuu and Ivo Vanderheyden and Professor R. De Hertogh},
  journal={Diabetologia},
  year={1994},
  volume={37},
  pages={855-862}
}
Embryos were recovered from diabetic rats on day 5 of pregnancy and incubated in vitro for up to 72 h. Compared to control embryos, blastocysts from diabetic rats showed a marked impairment in growth that resulted at 48 h in a higher rate of degeneration and a lower morphological score in the developing population. After 72 h in vitro, fewer developing blastocysts from diabetic rats formed trophoblastic outgrowths and fewer of those implanted developed an inner cell mass when compared with the… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Effect of diabetes mellitus on mouse preimplantation development

  • KH Moley, WK Vaughn, AH De Cherney, MP Diamond
  • J Reprod Fert
  • 1991
3 Excerpts

Similar Papers

Loading similar papers…