In vitro study of H+-sensitive neurons in the ventral medullary surface of neonate rats.

@article{Sugama1997InVS,
  title={In vitro study of H+-sensitive neurons in the ventral medullary surface of neonate rats.},
  author={Seiichi Sugama and Noriaki Shimokawa and Jiro Okada and Masami Miura},
  journal={Brain research},
  year={1997},
  volume={777 1-2},
  pages={95-102}
}
We hypothesized that the direct stimulus of the central chemoreceptor neurons is the CO2/H+-induced change in intracellular pH (pHi). If it is true, pHi responses during hypercapnic stimulation should be exhibited in the central chemoreceptor neurons in the ventral medullary surface (VMS) and some neurons in the CO2/H+ sensitive regions such as the nucleus tractus solitarii of the medial dorsal medulla (MDM). To test this hypothesis, the cultured VMS and MDM neurons (control) derived from one… CONTINUE READING