In vitro studies with the platelet-reactive antibody 50H.19 and its fragments.

@article{Shah1990InVS,
  title={In vitro studies with the platelet-reactive antibody 50H.19 and its fragments.},
  author={Vallabh O. Shah and Paul O. Zamora and Stephen L. Mills and Paul L Mann and Philip C. Comp},
  journal={Thrombosis research},
  year={1990},
  volume={58 5},
  pages={493-504}
}
The platelet-reactive monoclonal antibody 50H.19, its F(ab')2 fragments, and 99m-technetium (99m-Tc)-labeled fragments used in thrombus imaging were evaluated for their ability to cause platelet aggregation. The intact antibody caused a dose-dependent platelet aggregation in either platelet-rich plasma (PRP) or defined buffer solutions. The F(ab')2… CONTINUE READING