In vitro studies on mild alkali induced lesions in DNA.

@article{Musarrat1991InVS,
  title={In vitro studies on mild alkali induced lesions in DNA.},
  author={Javed Musarrat and M. Ghufran Ahmad},
  journal={Biochemistry international},
  year={1991},
  volume={25 2},
  pages={249-59}
}
S1 nuclease hydrolysis, benzoylated naphthoylated DEAE cellulose (BND-cellulose) chromatography as well as certain immunological and genetic techniques have been used to evaluate the effect of mild alkali (pH10.0) on the DNA molecule. Native calf thymus DNA after exposure to alkaline pH10.0 when subjected to S1 nuclease hydrolysis released significant… CONTINUE READING