In vitro studies on interferon-inducing capacity and sensitivity to IFN of human foamy virus.

@article{Sabile1996InVS,
  title={In vitro studies on interferon-inducing capacity and sensitivity to IFN of human foamy virus.},
  author={A. Sabile and A. Rhodes-Feuillette and F. Jaoui and J. Tobaly-Tapiero and M. Giron and J. Lasneret and J. Peries and M. Canivet},
  journal={Research in virology},
  year={1996},
  volume={147 1},
  pages={
          29-37
        }
}
  • A. Sabile, A. Rhodes-Feuillette, +5 authors M. Canivet
  • Published 1996
  • Biology, Medicine
  • Research in virology
  • We demonstrate in this article that human foamy virus (HFV) fails to induce interferon (IFN) production in two different human tissue culture cell lines: U373-MG and AV3. We also show the effect of human alpha-, beta- and gamma IFN on the multiplication cycle of HFV. Treatment of cells with 100 IU/ml of any IFN led to strong inhibition of an HFV-induced cytopathic effect. This effect was associated with a significant diminution of reverse transcriptase activity in supernatant fluids of IFN… CONTINUE READING
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