In vitro studies on interferon-inducing capacity and sensitivity to IFN of human foamy virus.

@article{Sabile1996InVS,
  title={In vitro studies on interferon-inducing capacity and sensitivity to IFN of human foamy virus.},
  author={Abdelmajid Sabile and Alice Rhodes-Feuillette and F Z Jaoui and Jo{\"e}lle Tobaly-Tapiero and M. L. Giron and J. Lasneret and Jorge Peries and Martine Canivet},
  journal={Research in virology},
  year={1996},
  volume={147 1},
  pages={
          29-37
        }
}
We demonstrate in this article that human foamy virus (HFV) fails to induce interferon (IFN) production in two different human tissue culture cell lines: U373-MG and AV3. We also show the effect of human alpha-, beta- and gamma IFN on the multiplication cycle of HFV. Treatment of cells with 100 IU/ml of any IFN led to strong inhibition of an HFV-induced cytopathic effect. This effect was associated with a significant diminution of reverse transcriptase activity in supernatant fluids of IFN… CONTINUE READING