In vitro studies: what is their role in toxicology?

  title={In vitro studies: what is their role in toxicology?},
  author={Robert B. Devlin and Mark L Frampton and Andrew J Ghio},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  volume={57 Suppl 1},
Many epidemiology studies have reported associations between inhaled environmental pollutants, especially particles, and mortality or morbidity. Despite these impressive associations, fundamental uncertainties exist as to the underlying pathophysiological mechanisms responsible for mortality or morbidity following exposure to air pollutants. In vitro toxicology provides a powerful approach to describe these mechanisms at the cellular, biochemical, and molecular level. This manuscript will… CONTINUE READING

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