In vitro stability, potency, and dissolution of duloxetine enteric-coated pellets after exposure to applesauce, apple juice, and chocolate pudding.

@article{Wells2008InVS,
  title={In vitro stability, potency, and dissolution of duloxetine enteric-coated pellets after exposure to applesauce, apple juice, and chocolate pudding.},
  author={Kevin A Wells and William G Losin},
  journal={Clinical therapeutics},
  year={2008},
  volume={30 7},
  pages={1300-8}
}
BACKGROUND Difficulty swallowing is a common problem in the clinical setting, particularly in elderly patients, and can significantly affect an individual's ability to maintain a proper level of nutrition. OBJECTIVE The purpose of this in vitro study was to determine if mixing duloxetine enteric-coated pellets in food substances is an acceptable alternative method for administering this oral formulation to patients with swallowing difficulties. METHODS To determine whether administration in… CONTINUE READING
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