In vitro spontaneous osteoclastogenesis of human peripheral blood mononuclear cells is not crucially dependent on T lymphocytes.

@article{Vandooren2009InVS,
  title={In vitro spontaneous osteoclastogenesis of human peripheral blood mononuclear cells is not crucially dependent on T lymphocytes.},
  author={Bernard Vandooren and Lode Melis and Eric M. Veys and Paul Peter Tak and D. Baeten},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={60 4},
  pages={1020-5}
}
OBJECTIVE In vitro spontaneous osteoclastogenesis from peripheral blood mononuclear cells (PBMCs) is increased in diseases with excessive bone loss. The purpose of this study was to reassess the role of T lymphocytes in this process. METHODS Fresh or cryopreserved PBMCs obtained from healthy subjects and from patients with rheumatoid arthritis, psoriatic… CONTINUE READING