In vitro sodium fluoride exposure decreases torsional and bending strength and increases ductility of mouse femora.

@article{Silva2000InVS,
  title={In vitro sodium fluoride exposure decreases torsional and bending strength and increases ductility of mouse femora.},
  author={M. J. Vaz-da Silva and S R Ulrich},
  journal={Journal of biomechanics},
  year={2000},
  volume={33 2},
  pages={231-4}
}
Fluoride exposure in vivo can reduce the material strength of bone, an effect that has been attributed to a change in mineral structure. An in vitro model of fluoride exposure offers the potential to study directly the effects of fluoride on bone mineral. Previous investigators have reported that soaking bones in sodium fluoride in vitro reduces bone strength. However, long soaking times and the absence of physiological buffering ions from their treatment solutions may have caused mineral… CONTINUE READING

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