In vitro sensitivity of human herpesvirus-6 to antiviral drugs.

  title={In vitro sensitivity of human herpesvirus-6 to antiviral drugs.},
  author={Henri Agut and H. Collandre and J. T. Aubin and Denise Gu{\'e}tard and V Favier and Didier Ingrand and Luc Montagnier and J. M. Huraux},
  journal={Research in virology},
  volume={140 3},
We studied the sensitivity of human herpesvirus-6 (HHV-6) to 4 antiviral drugs known to be effective in the treatment of infections with other human herpesviruses and human immunodeficiency virus. HHV-6 was grown in peripheral blood lymphocytes, and virus multiplication was quantified by evaluation of the cytopathic effect by molecular hybridization and indirect immunofluorescence assay. The 50% and 90% inhibitory concentrations (IC50 and IC90) were determined for each drug. The results… CONTINUE READING
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