In vitro secretion kinetics of proteins from Legionella pneumophila in comparison to proteins from non-pneumophila species.

Abstract

It has been shown that the loss of PilD, a prepilin peptidase necessary for type IV pilus biogenesis and establishment of the type II secretion apparatus is associated with loss of virulence in Legionella pneumophila. L. pneumophila is the species most frequently associated with Legionnaires' disease, but virulence factors unique to this species are not… (More)

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