In vitro search for synergy and antagonism: evaluation of docetaxel combinations in breast cancer cell lines

@article{Budman2002InVS,
  title={In vitro search for synergy and antagonism: evaluation of docetaxel combinations in breast cancer cell lines},
  author={Daniel R. Budman and Anthony Calabro},
  journal={Breast Cancer Research and Treatment},
  year={2002},
  volume={74},
  pages={41-46}
}
The use of combination chemotherapy is the accepted standard for most human malignancies but little attention has been paid to drug interactions. A combination of drugs may be synergistic, additive, or antagonistic in cytotoxic activity. This study evaluated combinations of agents with docetaxel, one of the most active agents in human breast cancer, using a median effects model to look at synergy or antagonism in vitro as a potential predictor of clinical outcome. Three human breast cancer cell… CONTINUE READING

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Treatment of advanced breast cancer with vinorelbine and docetaxel with or without human granulocyte colony-stimulating factor.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2001
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