In vitro screening for compounds derived from traditional chinese medicines with antiviral activities against porcine reproductive and respiratory syndrome virus.

@article{Cheng2013InVS,
  title={In vitro screening for compounds derived from traditional chinese medicines with antiviral activities against porcine reproductive and respiratory syndrome virus.},
  author={J. Cheng and N. Sun and X. Zhao and L. Niu and Meiqin Song and Yaogui Sun and Junbing Jiang and J. Guo and Yuansheng Bai and Junping He and H. Li},
  journal={Journal of microbiology and biotechnology},
  year={2013},
  volume={23 8},
  pages={
          1076-83
        }
}
  • J. Cheng, N. Sun, +8 authors H. Li
  • Published 2013
  • Biology, Medicine
  • Journal of microbiology and biotechnology
Seventeen compounds derived from traditional Chinese medicines (TCMs) were tested for their antiviral activity against porcine reproductive and respiratory syndrome virus (PRRSV) in vitro. Visualization with the cytopathologic effect (CPE) assay and the 3-(4, 5-dimethyithiazol- 2-yl)-2,5-diphenyltetrazolium bromide test were used to determine the 50% cytotoxic concentration (CC50) and 50% effective concentration (EC50) in cultured Marc-145 cells. Among the tested compounds, chlorogenic acid and… Expand
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