In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms

@article{Magalhes2008InVS,
  title={In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms},
  author={Lizandra Guidi Magalh{\~a}es and Carla Botelho Machado and Enyara R Morais and {\'E}rika Bueno de Carvalho Moreira and Cl{\'a}udia Sossai Soares and S{\'e}rgio Henrique Almeida da Silva and Ademar Alves da Silva Filho and Vanderlei Rodrigues},
  journal={Parasitology Research},
  year={2008},
  volume={104},
  pages={1197-1201}
}
The in vitro schistosomicidal activity of curcumin (doses ranging from 5 to 100 μM) was carried out against Schistosoma mansoni adult worms. Curcumin (at 50 and 100 μM) caused death of all worms. When tested at the doses of 5 and 20 μM, it decreased the worm viability in comparison with negative (Roswell Memorial Park Institute (RPMI) 1640 medium alone or RPMI 1640 medium with 10% dimethyl sulfoxide) and positive (heat-killed worms at 56°C or praziquantel 10 μM) control groups. All pairs of… CONTINUE READING

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In vitro antileishmanial and antimalarial activities of tetrahydrofuran lignans isolated from Nectandra megapotamica (Lauraceae)

  • AA Da Silva Filho, ES Costa, WR Cunha, MLA Silva, NPD Nanayakkara, JK Bastos
  • Phytother Res
  • 2008

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