In vitro release testing of matrices based on starch-methyl methacrylate copolymers: effect of tablet crushing force, dissolution medium pH and stirring rate.

Abstract

Direct-compressed matrix tablets were obtained from a variety of potato starch-methyl methacrylate copolymers(1) as sustained-release agents, using anhydrous theophylline as a model drug. The aim of this work was to investigate the influence of the copolymer type, the tablet crushing force and dissolution variables such as the pH of the dissolution medium… (More)
DOI: 10.1016/j.ijpharm.2013.12.001

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Cite this paper

@article{Ferrero2014InVR, title={In vitro release testing of matrices based on starch-methyl methacrylate copolymers: effect of tablet crushing force, dissolution medium pH and stirring rate.}, author={Carmen Ferrero and Mar{\'i}a Rosa Jim{\'e}nez-Castellanos}, journal={International journal of pharmaceutics}, year={2014}, volume={461 1-2}, pages={270-9} }