In vitro release of dimethyloxaloylglycine and l-mimosine from bovine bone mineral.

Abstract

OBJECTIVE Prolyl hydroxylases (PHD) are oxygen sensors and therefore pharmacological targets to stimulate periodontal regeneration. Here we evaluate the release profile of the PHD inhibitors dimethyloxaloylglycine and l-mimosine from bone substitutes. MATERIALS Dimethyloxaloylglycine and l-mimosine were lyophilised onto bone substitutes including bovine… (More)
DOI: 10.1016/j.archoralbio.2014.05.027

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