In-vitro release of acyclovir loaded Eudragit RLPO(®) nanoparticles for sustained drug delivery.

Abstract

In this present study the possibility to develop Eudragit RLPO(®) based nanoparticles of acyclovir was investigated in order to increase its efficacy because acyclovir has oral bioavailability of only 10-20% thus showing erratic absorption and bioavailability behaviour. The nanoparticles were prepared by nanoprecipitation technique. Pluronic F68 was used as… (More)
DOI: 10.1016/j.ijbiomac.2014.04.019

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