In vitro regulation of neural differentiation and axon growth by growth factors and bioactive nanofibers.

@article{Lam2010InVR,
  title={In vitro regulation of neural differentiation and axon growth by growth factors and bioactive nanofibers.},
  author={H. January Lam and Shyam A Patel and Aijun Wang and Julia Chu and Song Li},
  journal={Tissue engineering. Part A},
  year={2010},
  volume={16 8},
  pages={2641-8}
}
Human embryonic stem cell (ESC)-derived neural cells are a potential cell source for neural tissue regeneration. Understanding the biochemical and biophysical regulation of neural differentiation and axon growth will help us develop cell therapies and bioactive scaffolds. We demonstrated that basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) had different effects on human ESC differentiation into neural cells. EGF was more effective in inducing expression of neuron and… CONTINUE READING

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