In vitro reconstruction of a human capillary-like network in a tissue-engineered skin equivalent.

@article{Black1998InVR,
  title={In vitro reconstruction of a human capillary-like network in a tissue-engineered skin equivalent.},
  author={Annie F. Black and François Berthod and N. L'heureux and Lucie Germain and François A Auger},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1998},
  volume={12 13},
  pages={1331-40}
}
For patients with extensive burns, wound coverage with an autologous in vitro reconstructed skin made of both dermis and epidermis should be the best alternative to split-thickness graft. Unfortunately, various obstacles have delayed the widespread use of composite skin substitutes. Insufficient vascularization has been proposed as the most likely reason for their unreliable survival. Our purpose was to develop a vascular-like network inside tissue-engineered skin in order to improve graft… CONTINUE READING

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