In vitro radiosensitivity measured in lymphocytes and fibroblasts by colony formation and comet assay: comparison with clinical acute reactions to radiotherapy in breast cancer patients.

@article{Oppitz2002InVR,
  title={In vitro radiosensitivity measured in lymphocytes and fibroblasts by colony formation and comet assay: comparison with clinical acute reactions to radiotherapy in breast cancer patients.},
  author={Ulrich Oppitz and Stephanie Ricker Schulte and Helga Stopper and Karlheinz Baier and Michael Rolf Mueller and Jorn Wulf and Renate Schakowski and Michael Flentje},
  journal={International journal of radiation biology},
  year={2002},
  volume={78 7},
  pages={
          611-6
        }
}
PURPOSE To compare colony-forming and comet assays on fibroblasts and lymphocytes of 32 breast cancer patients irradiated after breast-conserving operations and to correlate the results with acute clinical radiation reactions in the skin. MATERIAL AND METHODS Skin fibroblasts were isolated and cultivated before radiotherapy and lymphocytes were drawn prior to the first and directly after the final external irradiation. The colony-forming assay was performed with fibroblasts and the comet… CONTINUE READING
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[Intrinsic radiosensitivity: predictive assays that will change daily practice].

  • Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
  • 2013
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