In vitro phenotypic differentiation towards commensal and pathogenic oral biofilms.

@article{Janus2015InVP,
  title={In vitro phenotypic differentiation towards commensal and pathogenic oral biofilms.},
  author={Marleen M Janus and Bart J. F. Keijser and Floris J Bikker and Rob A. M. Exterkate and Wim Crielaard and Bastiaan Philip Krom},
  journal={Biofouling},
  year={2015},
  volume={31 6},
  pages={503-10}
}
Commensal oral biofilms, defined by the absence of pathology-related phenotypes, are ubiquitously present. In contrast to pathological biofilms commensal biofilms are rarely studied. Here, the effect of the initial inoculum and subsequent growth conditions on in vitro oral biofilms was studied. Biofilms were inoculated with saliva and grown anaerobically for up to 21 days in McBain medium with or without fetal calf serum (FCS) or sucrose. Pathology-related phenotypes were quantified and the… CONTINUE READING
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