In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer.

@article{Jung2009InVP,
  title={In vitro pharmacogenomic database and chemosensitivity predictive genes in gastric cancer.},
  author={Jae-Joon Jung and Hei-Cheul Jeung and Hyun Cheol Chung and Jung Ok Lee and Tae Soo Kim and Yong Tai Kim and Sung Hoon Noh and Sun Young Rha},
  journal={Genomics},
  year={2009},
  volume={93 1},
  pages={52-61}
}
Gastric cancer is one of the most common cancers worldwide, and there are clinical caveats in predicting tumor response to chemotherapy. This study describes the construction of an in vitro pharmacogenomic database, and the selection of genes associated with chemosensitivity in gastric cancer cell lines. Gene expression and chemosensitivity databases were integrated using the Pearson correlation coefficient to give the GC-matrix. The 85 genes were selected that were commonly associated with… CONTINUE READING