In vitro pharmacodynamic profile of Loranthus ferrugineus: evidence for noncompetitive antagonism of norepinephrine-induced vascular contraction.

@article{Ameer2010InVP,
  title={In vitro pharmacodynamic profile of Loranthus ferrugineus: evidence for noncompetitive antagonism of norepinephrine-induced vascular contraction.},
  author={Omar Ziad Ameer and Ibrahim Muhammad Salman and Hafsa S Najim and Ghassan Zuhair Abdullah and Muthanna Fawzy Abdulkarim and Mun Fei Yam and Amirin Sadikun and Mohamed Z Asmawi},
  journal={Journal of acupuncture and meridian studies},
  year={2010},
  volume={3 4},
  pages={272-82}
}
The mode by which Loranthus ferrugineus methanol extract antagonizes and/or modulates norepinephrine-induced vasoconstriction was investigated in rat aortic rings. The vascular effects of three different concentrations of this extract were challenged against cumulative additions of norepinephrine. Phentolamine, a nonselective α-adrenoceptor antagonist, verapamil, an L-type calcium channel blocker, and papaverine, a phosphodiesterase inhibitor, were used in three different concentrations as… CONTINUE READING
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