In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery

@inproceedings{Abdullah2011InVP,
  title={In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery},
  author={Ghassan Zuhair Abdullah and Muthanna Fawzy Abdulkarim and Ibrahim M Salman and Omar Ziad Ameer and Mun Fei Yam and Ahmed Faisal Mutee and Mallikarjun Chitneni and Elrashid Saleh Mahdi and Mahiran Basri and Munavvar Zubaid Abdul Sattar and Azmin Mohd Noor},
  booktitle={International journal of nanomedicine},
  year={2011}
}
INTRODUCTION As a topical delivery system, a nanoscaled emulsion is considered a good carrier of several active ingredients that convey several side effects upon oral administration, such as nonsteroidal anti-inflammatory drugs (NSAIDs). OBJECTIVE We investigated the in vitro permeation properties and the in vivo pharmacodynamic activities of different nanoscaled emulsions containing ibuprofen, an NSAID, as an active ingredient and newly synthesized palm olein esters (POEs) as the oil phase… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES

pH, pK(a) and dermal delivery.

  • International journal of pharmaceutics
  • 2000
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Non-invasive in vivo methods for investigation of the skin barrier physical properties.

  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2009