In vitro osteogenic differentiation of marrow stromal cells encapsulated in biodegradable hydrogels.

@article{Temenoff2004InVO,
  title={In vitro osteogenic differentiation of marrow stromal cells encapsulated in biodegradable hydrogels.},
  author={Johnna S. Temenoff and Hansoo Park and Esmaiel Jabbari and Tiffany L. Sheffield and Richard G. LeBaron and Catherine G. Ambrose and Antonios G Mikos},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={70 2},
  pages={
          235-44
        }
}
Novel hydrogel materials based on oligo(poly(ethylene glycol) fumarate) (OPF) crosslinked with a redox radical initiation system were recently developed in our laboratory as injectable cell carriers for orthopedic tissue engineering applications. The effect of OPF hydrogel material properties on in vitro osteogenic differentiation of encapsulated rat marrow stromal cells (MSCs) with and without the presence of osteogenic supplements (dexamethasone) was investigated. Two OPF formulations that… CONTINUE READING

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