In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels.

@article{Nuttelman2004InVO,
  title={In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels.},
  author={Charles R Nuttelman and Margaret C Tripodi and Kristi S Anseth},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={68 4},
  pages={773-82}
}
Much research has focused on the differentiation of human mesenchymal stem cells (hMSCs) in monolayer culture; however, little is known about their differentiation potential in three-dimensional culture conditions. In this research, hMSCs were encapsulated in a photocrosslinkable, injectable scaffolding system based on poly(ethylene glycol) (PEG) hydrogels. To demonstrate the ability of hMSCs to differentiate in PEG hydrogels, cell/polymer constructs were cultured in osteogenic differentiation… CONTINUE READING