In vitro osteogenic differentiation of human mesenchymal stem cells and in vivo bone formation in composite nanofiber meshes.

@article{Ko2008InVO,
  title={In vitro osteogenic differentiation of human mesenchymal stem cells and in vivo bone formation in composite nanofiber meshes.},
  author={Eun Kyoung Ko and Sung In Jeong and Nae Gyune Rim and Young Moo Lee and Heungsoo Shin and B Lee},
  journal={Tissue engineering. Part A},
  year={2008},
  volume={14 12},
  pages={2105-19}
}
Tissue engineering has become an alternative method to traditional surgical treatments for the repair of bone defects, and an appropriate scaffold supporting bone formation is a key element in this approach. In the present study, nanofibrous organic and inorganic composite scaffolds containing nano-sized demineralized bone powders (DBPs) with biodegradable poly(L-lactide) (PLA) were developed using an electrospinning process for engineering bone. To assess their biocompatibility, in vitro… CONTINUE READING

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