In vitro networks: cortical mechanisms of anaesthetic action.

  title={In vitro networks: cortical mechanisms of anaesthetic action.},
  author={Bernd Antkowiak},
  journal={British journal of anaesthesia},
  volume={89 1},
Brain slices are well-established tools in neuroscience research. In the last decade scientists succeeded in isolating viable brain slices from many different regions of the mammalian central nervous system. The brain slice preparation was introduced by Henry MacIlwain in the 1950s. 45 46 Milestones in the development of this technique are listed in Table 1. Brain slices can be viewed as intact local microcircuits, lacking synaptic inputs from other parts of the central nervous system. In using… CONTINUE READING