In vitro modulation of antigen-primed T cells by a glycosylation-inhibiting factor that regulates the formation of antigen-specific suppressive factors ( antigen-specific suppressor T celis / lipocortin / IgE-suppressive factors )

  • M Iwata, KIMISHIGE ISHIZAKA Subdepartment
  • Published 2003
BDF1 [(C57BL/6 x DBA/2)F1] mice were primed with alum-absorbed ovalbumin, and their spleen cells were cultured with ovalbumin to activate antigen-primed T cells. The activated T cells were then propagated in interleukin 2-containing medium in the presence or absence of affinitypurified glycosylation-inhibiting factor (GIF). Upon incubation with ovalbumin… CONTINUE READING