In vitro model for contact sensitization: I. Stimulatory capacities of human blood-derived dendritic cells and their phenotypical alterations in the presence of contact sensitizers.

@article{Degwert1997InVM,
  title={In vitro model for contact sensitization: I. Stimulatory capacities of human blood-derived dendritic cells and their phenotypical alterations in the presence of contact sensitizers.},
  author={Joachim Degwert and F Steckel and U. Hoppe and Lorraine H. Kligman},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={1997},
  volume={11 5},
  pages={613-8}
}
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) located in many non-lymphoid tissues and a specialized form of DC-the Langerhans cell (LC)-is found in the skin. The functionality of LC as APC is crucial for the induction of an allergic contact dermatitis. For a long time LC research has been hampered by the limiting numbers of… CONTINUE READING