In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA.

@article{Obrien2013InVM,
  title={In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA.},
  author={Jason M O'brien and Andrew L. Williams and Carole Yauk and Doug Crump and Sean W. Kennedy},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2013},
  volume={27 6},
  pages={1649-58}
}
Perfluoroundecanoic acid (PFUdA) is one of the most highly detected perfluoroalkyl compounds in wild bird tissues and eggs. Although PFUdA does not affect hatching success, many PFCs are known to impair post-hatch development and survival. Here we use microarrays to survey the transcriptional response of cultured chicken embryonic hepatocytes (CEH) to PFUdA… CONTINUE READING