In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes.

@article{Crowell2014InVM,
  title={In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes.},
  author={Susan Ritger Crowell and Sesha Hanson-Drury and David Edward Williams and Richard A. Corley},
  journal={Toxicology letters},
  year={2014},
  volume={228 1},
  pages={48-55}
}
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous and often carcinogenic contaminants released into the environment during natural and anthropogenic combustion processes. Benzo[a]pyrene (B[a]P) is the prototypical carcinogenic PAH, and dibenzo[def,p]chrysene (DBC) is a less prevalent, but highly potent transplacental carcinogenic PAH. Both are… CONTINUE READING