In vitro mechanical loading models for periodontal ligament cells: from two-dimensional to three-dimensional models.

@article{Yang2015InVM,
  title={In vitro mechanical loading models for periodontal ligament cells: from two-dimensional to three-dimensional models.},
  author={Liang Yang and Yan Yang and Shuai Wang and Yu Li and Zhihe Zhao},
  journal={Archives of oral biology},
  year={2015},
  volume={60 3},
  pages={
          416-24
        }
}
Periodontal ligament cells (PDLCs) respond to various mechanical stimuli, including mastication and orthodontic force, and thereby play an important functional role. A number of in vitro models have been widely used to study these mechanoresponses. Here, we comprehensively review the various in vitro mechanical loading approaches used for assessing PDLCs, including their force generation properties, mechanical characteristics, and simulation of authentic bioprocesses. Furthermore, we highlight… CONTINUE READING

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The microRNA 132 regulates fluid shear stress-induced differentiation in periodontal ligament cells through mTOR signaling pathway.

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