In vitro investigation of the genotoxic and cytotoxic effects of thiacloprid in cultured human peripheral blood lymphocytes.

@article{Kocaman2014InVI,
  title={In vitro investigation of the genotoxic and cytotoxic effects of thiacloprid in cultured human peripheral blood lymphocytes.},
  author={Ayşe Yavuz Kocaman and Eyy{\"u}p Renc{\"u}zoğulları and Mehmet Topaktaş},
  journal={Environmental toxicology},
  year={2014},
  volume={29 6},
  pages={631-41}
}
Thiacloprid, a neonicotinoid insecticide, is widely used for controlling various species of pests on many crops. The potential genotoxic effects of thiacloprid on human peripheral blood lymphocytes (PBLs) were investigated in vitro by the chromosome aberrations (CAs), sister chromatid exchanges (SCEs), and cytokinesis-block micronucleus (MN) assays. The human PBLs were treated with 75, 150, and 300 μg/mL thiacloprid in the absence and presence of an exogenous metabolic activator (S9 mix… CONTINUE READING
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