In vitro invasiveness of human breast cancer cells is promoted by low density lipoprotein receptor-related protein.

@article{Li1998InVI,
  title={In vitro invasiveness of human breast cancer cells is promoted by low density lipoprotein receptor-related protein.},
  author={Yong Li and Nancy Wood and P G Grimsley and David Yellowlees and Peter K Donnelly},
  journal={Invasion & metastasis},
  year={1998},
  volume={18 5-6},
  pages={240-51}
}
Low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor (LRP) is a surface membrane endocytic receptor, one of whose many functions is the regulation of plasminogen activator-mediated cell migration. LRP is known to have a role in migration and invasion, but its direct involvement has been demonstrated only in non-tumour cells. We investigated six breast cancer cell lines and a normal mammary epithelial cell clone for surface and total cellular LRP expression, and… CONTINUE READING