In vitro induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in keratinocytes by boron and manganese.

@article{Chebassier2004InVI,
  title={In vitro induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in keratinocytes by boron and manganese.},
  author={Nathalie Chebassier and Ouijja El Houssein and Isabelle Viegas and Brigitte Dr{\'e}no},
  journal={Experimental dermatology},
  year={2004},
  volume={13 8},
  pages={484-90}
}
Matrix metalloproteinase (MMP)-2 and MMP-9 are involved in keratinocyte migration and granulation tissue remodeling during wound healing. Thermal water cures are sometimes proposed as complementary treatment for accelerating healing of wounds resulting from burns and/or surgery, but their mechanisms of action remain unknown. Some thermal waters are rich in trace elements such as boron and manganese. Interestingly, clinical studies have shown the beneficial effects of trace elements such as… CONTINUE READING

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