In vitro heparan sulfate modulates the immune responses of normal and tumor-bearing mice.

@article{Rashid2007InVH,
  title={In vitro heparan sulfate modulates the immune responses of normal and tumor-bearing mice.},
  author={Rashid M Rashid and John C. M. Lee and Jawed Fareed and M Rita I Young},
  journal={Immunological investigations},
  year={2007},
  volume={36 2},
  pages={183-201}
}
Tumor-bearing (TB) patients and TB animal models show a wide array of immunologic deficits. Heparan sulfate (HS) has been shown to both improve immune cell proliferative responses and to induce Th1 cytokine responses in normal animals. These HS effects, if harnessed, would be of great benefit to TB patients. The present study focused on replicating previous… CONTINUE READING