In vitro gentamicin release from commercially available calcium-phosphate bone substitutes influence of carrier type on duration of the release profile

@article{Stallmann2006InVG,
  title={In vitro gentamicin release from commercially available calcium-phosphate bone substitutes influence of carrier type on duration of the release profile},
  author={Hein P Stallmann and Chris Faber and Antonius L. J. J. Bronckers and Arie V Nieuw Amerongen and Paul I. J. M. Wuisman},
  journal={BMC Musculoskeletal Disorders},
  year={2006},
  volume={7},
  pages={18 - 18}
}
BACKGROUND Polymethyl-methacrylate (PMMA) beads releasing antibiotics are used extensively to treat osteomyelitis, but require surgical removal afterwards because they do not degrade. METHODS As an alternative option, this report compares the in vitro gentamicin release profile from clinically used, biodegradable carrier-materials: six injectable cements and six granule-types. Cement cylinders and coated granules containing 3% gentamicin were submerged in dH2O and placed in a 48-sample… CONTINUE READING

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