In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

@inproceedings{Doak2012InVG,
  title={In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines},
  author={Shareen Heather Doak and Bella B Manshian and G.J.S. Jenkins and Narendra Singh},
  booktitle={Mutation research},
  year={2012}
}
There is a pressing requirement to define a hazard identification and risk management strategy for nanomaterials due to the rapid growth in the nanotechnology industry and their promise of life-style revolutions through the development of wide-ranging nano-containing consumer products. Consequently, a battery of well defined and appropriate in vitro assays to assess a number of genotoxicity endpoints is required to minimise extensive and costly in vivo testing. However, the validity of the… CONTINUE READING