In vitro evaluation of transdermal nicotine delivery systems commercially available in Brazil

@inproceedings{Ruela2013InVE,
  title={In vitro evaluation of transdermal nicotine delivery systems commercially available in Brazil},
  author={Andr{\'e} Lu{\'i}s Morais Ruela and Eduardo da Costa Figueiredo and Aline Gravinez Perissinato and Ana Carolina and Zogbi Lima and Magali Benjamim de Ara{\'u}jo and Gislaine Ribeiro Pereira},
  year={2013}
}
The aim of this study was to develop and validate a method for evaluating the release and skin permeation from transdermal nicotine patches using the vertical diffusion cell (VDC). The VDC is an experimental apparatus employed in research, development, and the pharmaceutical field because it can simulate conditions closest to those established in clinical trials. Two transdermal nicotine delivery systems marketed in Brazil to release 14 mg over 24 hours were evaluated. Release studies were… CONTINUE READING
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