In vitro evaluation of the mucoadhesive properties of polysaccharide-based nanoparticulate oral drug delivery systems.

@article{Chayed2007InVE,
  title={In vitro evaluation of the mucoadhesive properties of polysaccharide-based nanoparticulate oral drug delivery systems.},
  author={Siwar Chayed and Françoise M Winnik},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2007},
  volume={65 3},
  pages={363-70}
}
Impedance quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) measurements were performed in order to assess the mucoadhesive properties of hydrophobically modified (HM) derivatives of dextran (DEX), with an average molecular weight of 10,000 Da, and of hydroxypropylcellulose (HPC), with an average molecular weight of 80,000 Da. The measurements involved (1) treatment of a hydrophobic surface with bovine submaxillary gland mucin (BSM) under various pH conditions (2.0-8.0) and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Methods to determine the interactions of micro- and nanoparticles with mucus.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V • 2015
View 1 Excerpt

Similar Papers

Loading similar papers…