In vitro evaluation of biopolymers as delivery system of plant extracts on cultures of Porphyromonas gingivalis and Agreggatibacter actinomycetemcomitans

  title={In vitro evaluation of biopolymers as delivery system of plant extracts on cultures of Porphyromonas gingivalis and Agreggatibacter actinomycetemcomitans},
  author={A. Rodr{\'i}guez Garc{\'i}a and Luis Jes{\'u}s Gal{\'a}n Wong and Julia Verde Star and M. S. Flores Gonz{\'a}lez and Katiushka Ar{\'e}valo Ni{\~n}o},
Periodontal disease is an infectious and inflamatory process that affects the periodontum including the gingiva, gingival attachment, periodontal ligament, cementum and supporting alveolar bone, and is the major cause of tooth loss in adults. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, have been identified as causative agents. Therapy includes oral hygiene education, instrumentation for removal of calculus (scaling), chemotherapy and periodontal surgery. At recent years… 


Subgingival microflora and periodontal disease.
  • J. Slots
  • Medicine, Biology
    Journal of clinical periodontology
  • 1979
The available data on oral microbial ecology suggest that the presence of dental plaque containing Gram-positive organisms may be essential for the attachment and colonization of several Gram-negative species after their initial introduction into the mouth and the periodontal pocket area.
Periodontal therapy in humans. I. Microbiological and clinical effects of a single course of periodontal scaling and root planing, and of adjunctive tetracycline therapy.
The present results showed that maarked and long-lasting changes in the subgingival microflora associated with periodontal disease could be achieved by a single course of periodontal treatment.
Activity of Chitosans in combination with antibiotics in Pseudomonas aeruginosa
The findings suggest on the use of chitosans as enhancing agent in combination with antibiotics in pharmaceutical preparations as well as the possible role of this efflux pump in Sulfamethoxazole efflux.
The predominant cultivable organisms in juvenile periodontitis.
  • J. Slots
  • Medicine, Biology
    Scandinavian journal of dental research
  • 1976
Quantitative and qualitative examinations of the predominant cultivable microflora of the advanced tissue destruction (pocket) associated with juvenile periodontitis and of control pockets without
Plant Products as Antimicrobial Agents
The current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity, are summarized and the structure and antimicrobial properties of phytochemicals are addressed.
Safety studies of a novel starch, pullulan: chronic toxicity in rats and bacterial mutagenicity.
  • T. Kimoto, T. Shibuya, S. Shiobara
  • Biology, Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1997
Industrial Gums: Polysaccharides and Their Derivatives
R.L. Whistler, Introduction to Industrial Gums. I.M. Dea, Conformational Origins of Polysaccharide Solution and Gel Properties. G.A. Towle and R.L. Whistler, Chemical Modification of Gums. I.W.