In vitro evaluation of Spirulina platensis extract incorporated skin cream with its wound healing and antioxidant activities

@article{Gunes2017InVE,
  title={In vitro evaluation of Spirulina platensis extract incorporated skin cream with its wound healing and antioxidant activities},
  author={Seda Gunes and Sedef Tamburaci and Meltem Conk Dalay and İsmet Deliloglu Gurhan},
  journal={Pharmaceutical Biology},
  year={2017},
  volume={55},
  pages={1824 - 1832}
}
CONTEXT Algae have gained importance in cosmeceutical product development due to their beneficial effects on skin health and therapeutical value with bioactive compounds. [...] Key Method Crude extracts were incorporated in skin cream formulation at 0.01% (w/w) concentration and in vitro wound healing and genotoxicity studies were performed. Immunohistochemical staining was performed to determine the collagen activity. RESULTS 0.1% S. platensis extract exhibited higher proliferation activity compared with the…Expand
EVALUATION OF ANTIOXIDANT AND WOUND HEALING ACTIVITIES OF Spirulina sp. EXTRACT
Spirulina spp. is an alga from phylum Cyanobacteria that have multi-benefit due to their potential compounds like protein, carbohydrate, lipid, mineral, pigment, and phenolic compounds. Several typesExpand
Formulation of Creams Containing Spirulina Platensis Powder with Different Nonionic Surfactants for the Treatment of Acne Vulgaris
TLDR
Formulations containing SP 70 surfactant with TC showed the most favorable dissolution profiles and were found to be nontoxic, and showed significant increase in free radical scavenger activity compared to the blank sample and the highest SOD enzyme activity was also detected after treatment with the cream samples. Expand
Spirulina maxima derived marine pectin promotes the in vitro and in vivo regeneration and wound healing in zebrafish.
TLDR
Investigation of the regenerative and wound healing activities of a Spirulina (Arthrospira) maxima based pectin (SmP) using in vitro human dermal fibroblasts and in vivo zebrafish model supported the rapid epidermal growth and tissue remodeling in SmP treated fish, suggesting that SmP exerts positive effects associated with wound healing. Expand
Spirulina for Skin Care: A Bright Blue Future
TLDR
In this review, recent cosmetic applications of Spirulina are revised, by highlighting its ability in improving skin appearance and health, and the analysis of thespirulina cosmetic benchmark is discussed. Expand
Arthrospira Platensis – Potential in Dermatology and Beyond
TLDR
It could be demonstrated, that AP has significant antioxidant activity, prevents viruses from entry into target cells and inhibits the colonisation of wounds by multi-resistant bacteria, and anti-cancer activity was documented in models of oral cancer, melanoma, and UV-induced non-melanoma skin cancer. Expand
Study the antioxidant effects of blue-green algae Spirulina extract on ROS and MDA production in human lung cancer cells
TLDR
According to the higher production of ROS and MDA in treated A549 cancer cell lines, it could be concluded that this algal extract could be considered as a natural product with anticancer activity against lung cancer cells. Expand
Treatment with Modified Extracts of the Microalga Planktochlorella nurekis Attenuates the Development of Stress-Induced Senescence in Human Skin Cells
TLDR
It is postulate that selected microalgal extracts of Planktochlorella nurekis can be considered to be used in skin anti-aging therapy and reduced the development of oxidative stress-induced senescence in skin cells. Expand
Carboxyethyl aminobutyric acid (CEGABA) lacks cytotoxicity and genotoxicity and stimulates cell proliferation and migration in vitro
TLDR
The time-dependent proliferation and migration of fibroblasts induced by CEGABA besides the fact that the compound is neither genotoxic nor cytotoxic makes it an ideal candidate in the development of cosmeceuticals in antiaging therapy. Expand
Study on Extracting Crude Phycocyanin from Spirulina Algae and Determining Its Ability in Protecting Fibroblasts from Oxidative Stress of Hydroxyl Peroxide
Phycocyanin is a powerful natural antioxidant from Arthrospira platensis. In this study, crude phycocyanin (crPC) was extracted, and its ability to protect fibroblast from hydroxyl peroxide (H2O2) inExpand
Application of microalgae and microalgal bioactive compounds in skin regeneration
Abstract The search for natural products with benefits for skin regeneration has gained a much broader interest worldwide. Microalgae represent a natural source of interesting bioactive compoundsExpand
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