In vitro establishment of AIDS-related lymphoma cell lines: phenotypic characterization, oncogene and tumor suppressor gene lesions, and heterogeneity in Epstein-Barr virus infection.

@article{Gaidano1993InVE,
  title={In vitro establishment of AIDS-related lymphoma cell lines: phenotypic characterization, oncogene and tumor suppressor gene lesions, and heterogeneity in Epstein-Barr virus infection.},
  author={Gianluca Gaidano and Nasser Z. Parsa and Virginia Tassi and Phyllis A. Della-Latta and Raju S. K. Chaganti and Daniel M. Knowles and Riccardo Dalla-Favera},
  journal={Leukemia},
  year={1993},
  volume={7 10},
  pages={1621-9}
}
Lymphoma represents a major source of morbidity and mortality among AIDS patients. AIDS-associated non-Hodgkin lymphomas (AIDS-NHL) are almost invariably B-cell derived, are classified as high or intermediate grade lymphomas, and display three main histologic types: namely, small non-cleaved cell lymphoma (SNCCL), large cell immunoblastic plasmacytoid lymphoma (LC-IBPL), and large cell lymphoma (LCL). Here we report the in vitro establishment of three new AIDS-NHL cell lines (termed HBL-1, HBL… CONTINUE READING

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